Carpi — San Luca, 198,7 км |
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| 1 | Enric Mas Nicolau | (Esp) | Movistar Team | 04:55:31 |
| 2 | Tadej Pogačar | (Slo) | Uae Team Emirates | 0:00:11 |
| 3 | Domenico Pozzovivo | (Ita) | Intermarché — Wanty — Gobert Matériaux | 0:00:14 |
| 4 | Alejandro Valverde | (Esp) | Movistar Team | 0:00:26 |
| 5 | Rigoberto Uran | (Col) | Ef Education — Easypost | 0:00:31 |
| 6 | Lorenzo Fortunato | (Ita) | Eolo-Kometa Cycling Team | 0:00:37 |
| 7 | Ruben Fernandez | (Esp) | Cofidis | 0:00:46 |
| 8 | Rudy Molard | (Fra) | Groupama — Fdj | 0:00:53 |
| 9 | Davide Formolo | (Ita) | Uae Team Emirates | 0:01:12 |
| 10 | Michael Storer | (Aus) | Groupama — Fdj | 0:01:13 |
| 11 | Mark Padun | (Ukr) | Ef Education — Easypost | 0:01:36 |
| 12 | Diego Ulissi | (Ita) | Uae Team Emirates | 0:01:44 |
| 13 | Andrea Piccolo | (Ita) | Ef Education — Easypost | |
| 14 | Ivan Ramiro Sosa Cuervo | (Col) | Movistar Team | 0:01:47 |
| 15 | Ilan Van Wilder | (Bel) | Quick-Step Alpha Vinyl Team | 0:02:04 |
| 16 | Carlos Rodriguez Cano | (Esp) | Ineos Grenadiers | |
| 17 | Thomas Gloag | (Gbr) | Trinity Racing | 0:02:08 |
| 18 | Lorenzo Rota | (Ita) | Intermarché — Wanty — Gobert Matériaux | 0:02:14 |
| 19 | Clément Berthet | (Fra) | Ag2R Citroen Team | 0:02:20 |
| 20 | Kévin Vauquelin | (Fra) | Team Arkea — Samsic | 0:02:43 |
| 21 | Simone Velasco | (Ita) | Astana Qazaqstan Team | 0:03:15 |
| 22 | Pierre Latour | (Fra) | Totalenergies | 0:03:16 |
| 23 | Alexis Vuillermoz | (Fra) | Totalenergies | 0:03:18 |
| 24 | Aleksandr Vlasov | (Rus) | Bora — Hansgrohe | 0:03:22 |
| 25 | Sjoerd Bax | (Ned) | Alpecin-Deceuninck | 0:03:28 |
| 26 | Odd Christian Eiking | (Nor) | Ef Education — Easypost | 0:03:29 |
| 27 | Alessandro De Marchi | (Ita) | Israel — Premier Tech | |
| 28 | Sam Oomen | (Ned) | Jumbo-Visma | 0:03:32 |
| 29 | Robert Gesink | (Ned) | Jumbo-Visma | |
| 30 | Daniel Felipe Martinez Poveda | (Col) | Ineos Grenadiers | |
| 31 | Jhoan Esteban Chaves Rubio | (Col) | Ef Education — Easypost | |
| 32 | Carl Fredrik Hagen | (Nor) | Israel — Premier Tech | |
| 33 | Chris Harper | (Aus) | Jumbo-Visma | 0:03:42 |
| 34 | Jon Agirre Egaña | (Esp) | Equipo Kern Pharma | 0:03:47 |
| 35 | Giovanni Aleotti | (Ita) | Bora — Hansgrohe | 0:03:56 |
| 36 | Maxim Van Gils | (Bel) | Lotto Soudal | 0:04:13 |
| 37 | David Gaudu | (Fra) | Groupama — Fdj | 0:04:20 |
| 38 | Mauri Vansevenant | (Bel) | Quick-Step Alpha Vinyl Team | 0:04:22 |
| 39 | Einer Augusto Rubio Reyes | (Col) | Movistar Team | 0:04:28 |
| 40 | Kevin Colleoni | (Ita) | Team Bikeexchange — Jayco | 0:04:33 |
| 41 | Jan Bakelants | (Bel) | Intermarché — Wanty — Gobert Matériaux | 0:04:42 |
| 42 | Simone Petilli | (Ita) | Intermarché — Wanty — Gobert Matériaux | 0:04:44 |
| 43 | Mathieu Burgaudeau | (Fra) | Totalenergies | 0:04:59 |
| 44 | Davide Bais | (Ita) | Eolo-Kometa Cycling Team | 0:05:01 |
| 45 | Nicola Conci | (Ita) | Alpecin-Deceuninck Development Team | 0:05:23 |
| 46 | Michel Ries | (Lux) | Team Arkea — Samsic | 0:05:34 |
| 47 | Marco Tizza | (Ita) | Bingoal Pauwels Sauces Wb | 0:05:59 |
| 48 | Tao Geoghegan Hart | (Gbr) | Ineos Grenadiers | 0:06:03 |
| 49 | Filippo Zana | (Ita) | Bardiani Csf Faizane’ | |
| 50 | Alan Jousseaume | (Fra) | Totalenergies | |
| 51 | Guillaume Martin | (Fra) | Cofidis | |
| 52 | Miguel Angel Lopez Moreno | (Col) | Astana Qazaqstan Team | |
| 53 | Rafal Majka | (Pol) | Uae Team Emirates | |
| 54 | Simon Clarke | (Aus) | Israel — Premier Tech | |
| 55 | Marc Hirschi | (Sui) | Uae Team Emirates | |
| 56 | Aurélien Paret Peintre | (Fra) | Ag2R Citroen Team | |
| 57 | Jesus Herrada | (Esp) | Cofidis | |
| 58 | Giovanni Carboni | (Ita) | Equipo Kern Pharma | 0:06:28 |
| 59 | Kenny Elissonde | (Fra) | Trek — Segafredo | 0:07:03 |
| 60 | Romain Gregoire | (Fra) | Groupama — Fdj | 0:07:11 |
| 61 | Mattia Bais | (Ita) | Drone Hopper — Androni Giocattoli | 0:07:38 |
| 62 | Luca Covili | (Ita) | Bardiani Csf Faizane’ | |
| 63 | Matteo Fabbro | (Ita) | Bora — Hansgrohe | 0:07:39 |
| 64 | Hector Carretero | (Esp) | Equipo Kern Pharma | 0:08:01 |
| 65 | Davide De Pretto | (Ita) | Zalf Euromobil Fior | 0:08:41 |
| 66 | Clément Champoussin | (Fra) | Ag2R Citroen Team | 0:09:06 |
| 67 | Omar El Gouzi | (Ita) | Bardiani Csf Faizane’ | 0:09:13 |
| 68 | Alessandro Bisolti | (Ita) | Drone Hopper — Androni Giocattoli | |
| 69 | Calum Johnston | (Gbr) | Caja Rural-Seguros Rga | |
| 70 | Louis Barre | (Fra) | Team Arkea — Samsic | |
| 71 | Jaakko Hänninen | (Fin) | Ag2R Citroen Team | |
| 72 | Victor De La Parte | (Esp) | Totalenergies | |
| 73 | Paul Ourselin | (Fra) | Totalenergies | |
| 74 | Joel Nicolau Beltran | (Esp) | Caja Rural-Seguros Rga | |
| 75 | Jose Felix Parra Cuerda | (Esp) | Equipo Kern Pharma | |
| 76 | Per Strand Hagenes | (Nor) | Jumbo-Visma Development Team | |
| 77 | Kobe Goossens | (Bel) | Intermarché — Wanty — Gobert Matériaux | 0:09:44 |
| 78 | Simone Ravanelli | (Ita) | Drone Hopper — Androni Giocattoli | 0:09:48 |
| 79 | Carlos Barbero | (Esp) | Lotto Soudal | 0:10:23 |
| 80 | Julien Bernard | (Fra) | Trek — Segafredo | |
| 81 | Julian Alaphilippe | (Fra) | Quick-Step Alpha Vinyl Team | 0:10:26 |
| 82 | Natnael Tesfazion | (Eri) | Drone Hopper — Androni Giocattoli | |
| 83 | Umberto Marengo | (Ita) | Drone Hopper — Androni Giocattoli | 0:10:44 |
| 84 | Ion Izaguirre Insausti | (Esp) | Cofidis | 0:11:12 |
| 85 | Remy Mertz | (Bel) | Bingoal Pauwels Sauces Wb | 0:11:22 |
| 86 | Simon Guglielmi | (Fra) | Team Arkea — Samsic | 0:11:40 |
| 87 | Geoffrey Bouchard | (Fra) | Ag2R Citroen Team | |
| DNF | Samuele Zoccarato | (Ita) | Bardiani Csf Faizane’ | |
| DNF | Enrico Battaglin | (Ita) | Bardiani Csf Faizane’ | |
| DNF | Luca Rastelli | (Ita) | Bardiani Csf Faizane’ | |
| DNF | Henok Mulueberhan | (Eri) | Bardiani Csf Faizane’ | |
| DNF | Paul Lapeira | (Fra) | Ag2R Citroen Team | |
| DNF | Valentin Paret Peintre | (Fra) | Ag2R Citroen Team | |
| DNF | Cristian Scaroni | (Ita) | Astana Qazaqstan Team | |
| DNF | Javier Romo Oliver | (Esp) | Astana Qazaqstan Team | |
| DNF | Stefan De Bod | (Rsa) | Astana Qazaqstan Team | |
| DNF | Samuele Battistella | (Ita) | Astana Qazaqstan Team | |
| DNF | David De La Cruz Melgarejo | (Esp) | Astana Qazaqstan Team | |
| DNF | Wilco Kelderman | (Ned) | Bora — Hansgrohe | |
| DNF | Emanuel Buchmann | (Ger) | Bora — Hansgrohe | |
| DNF | Cesare Benedetti | (Pol) | Bora — Hansgrohe | |
| DNF | Patrick Konrad | (Aut) | Bora — Hansgrohe | |
| DNF | Rémy Rochas | (Fra) | Cofidis | |
| DNF | François Bidard | (Fra) | Cofidis | |
| DNF | Davide Villella | (Ita) | Cofidis | |
| DNF | Diego Andres Camargo Pineda | (Col) | Ef Education — Easypost | |
| DNF | Jefferson Cepeda | (Ecu) | Ef Education — Easypost | |
| DNF | Jacopo Guarnieri | (Ita) | Groupama — Fdj | |
| DNF | Matthieu Ladagnous | (Fra) | Groupama — Fdj | |
| DNF | Lars Van Den Berg | (Ned) | Groupama — Fdj | |
| DNF | Leo Hayter | (Gbr) | Hagens Berman Axeon | |
| DNF | Laurens De Plus | (Bel) | Ineos Grenadiers | |
| DNF | Adam Yates | (Gbr) | Ineos Grenadiers | |
| DNF | Jhonatan Manuel Narvaez Prado | (Ecu) | Ineos Grenadiers | |
| DNF | Rein Taaramäe | (Est) | Intermarché — Wanty — Gobert Matériaux | |
| DNF | Laurens Huys | (Bel) | Intermarché — Wanty — Gobert Matériaux | |
| DNF | Dylan Teuns | (Bel) | Israel — Premier Tech | |
| DNF | Michael Woods | (Can) | Israel — Premier Tech | |
| DNF | Jakob Fuglsang | (Den) | Israel — Premier Tech | |
| DNF | Corbin Strong | (Nzl) | Israel — Premier Tech | |
| DNF | Rick Pluimers | (Ned) | Jumbo-Visma Development Team | |
| DNF | Tobias S. Foss | (Nor) | Jumbo-Visma | |
| DNF | Filippo Conca | (Ita) | Lotto Soudal | |
| DNF | Andreas Kron | (Den) | Lotto Soudal | |
| DNF | Kamil Malecki | (Pol) | Lotto Soudal | |
| DNF | Viktor Verschaeve | (Bel) | Lotto Soudal | |
| DNF | Harm Vanhoucke | (Bel) | Lotto Soudal | |
| DNF | Jorge Arcas | (Esp) | Movistar Team | |
| DNF | José Rojas | (Esp) | Movistar Team | |
| DNF | Matteo Jorgenson | (Usa) | Movistar Team | |
| DNF | Dries Devenyns | (Bel) | Quick-Step Alpha Vinyl Team | |
| DNF | James Knox | (Gbr) | Quick-Step Alpha Vinyl Team | |
| DNF | Tim Declercq | (Bel) | Quick-Step Alpha Vinyl Team | |
| DNF | Louis Vervaeke | (Bel) | Quick-Step Alpha Vinyl Team | |
| DNF | Tanel Kangert | (Est) | Team Bikeexchange — Jayco | |
| DNF | Simon Philip Yates | (Gbr) | Team Bikeexchange — Jayco | |
| DNF | Damien Howson | (Aus) | Team Bikeexchange — Jayco | |
| DNF | Tsgabu Gebremaryam Grmay | (Eth) | Team Bikeexchange — Jayco | |
| DNF | Jan Maas | (Ned) | Team Bikeexchange — Jayco | |
| DNF | Amanuel Gehbreigzabhier | (Eri) | Trek — Segafredo | |
| DNF | Giulio Ciccone | (Ita) | Trek — Segafredo | |
| DNF | Dario Cataldo | (Ita) | Trek — Segafredo | |
| DNF | Asbjørn Hellemose | (Den) | Trek — Segafredo | |
| DNF | Mathias Vacek | (Cze) | Trek — Segafredo | |
| DNF | Alessandro Covi | (Ita) | Uae Team Emirates | |
| DNF | George Bennett | (Nzl) | Uae Team Emirates | |
| DNF | Robert Stannard | (Aus) | Alpecin-Deceuninck | |
| DNF | Xandro Meurisse | (Bel) | Alpecin-Deceuninck | |
| DNF | Jimmy Janssens | (Bel) | Alpecin-Deceuninck | |
| DNF | Jay Vine | (Aus) | Alpecin-Deceuninck | |
| DNF | Alex Bogna | (Aus) | Alpecin-Deceuninck Development Team | |
| DNF | Julien Desmarets | (Bel) | Bingoal Pauwels Sauces Wb | |
| DNF | Dimitri Peyskens | (Bel) | Bingoal Pauwels Sauces Wb | |
| DNF | Johan Meens | (Bel) | Bingoal Pauwels Sauces Wb | |
| DNF | Arjen Livyns | (Bel) | Bingoal Pauwels Sauces Wb | |
| DNF | Tom Paquot | (Bel) | Bingoal Pauwels Sauces Wb | |
| DNF | Andoni Lopez De Abetxuko Jimenez | (Esp) | Caja Rural-Seguros Rga | |
| DNF | Jon Barrenetxea Golzarri | (Esp) | Caja Rural-Seguros Rga | |
| DNF | Jefferson Cepeda | (Ecu) | Caja Rural-Seguros Rga | |
| DNF | Jhojan Orlando Garcia Susa | (Col) | Caja Rural-Seguros Rga | |
| DNF | Josu Etxeberria Azpilikueta | (Esp) | Caja Rural-Seguros Rga | |
| DNF | Abner Santiago Umba Lopez | (Col) | Drone Hopper — Androni Giocattoli | |
| DNF | Edoardo Zardini | (Ita) | Drone Hopper — Androni Giocattoli | |
| DNF | Edward Ravasi | (Ita) | Eolo-Kometa Cycling Team | |
| DNF | Erik Fetter | (Hun) | Eolo-Kometa Cycling Team | |
| DNF | Francesco Gavazzi | (Ita) | Eolo-Kometa Cycling Team | |
| DNF | Diego Pablo Sevilla Lopez | (Esp) | Eolo-Kometa Cycling Team | |
| DNF | Andrea Montoli | (Ita) | Eolo-Kometa Cycling Team | |
| DNF | Roger Adria Oliveras | (Esp) | Equipo Kern Pharma | |
| DNF | Ivan Moreno Sanchez | (Esp) | Equipo Kern Pharma | |
| DNF | Igor Arrieta Lizarraga | (Esp) | Equipo Kern Pharma | |
| DNF | Maxime Bouet | (Fra) | Team Arkea — Samsic | |
| DNF | Elie Gesbert | (Fra) | Team Arkea — Samsic | |
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