Zuidwolde — Hoogeveen, 165,7 км |
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| 1 | Marta Bastianelli | (Ita) | Team Virtu Cycling | 4:24:14 |
| 2 | Chantal Blaak | (Ned) | Boels Dolmans Cyclingteam | |
| 3 | Ellen Van Dijk | (Ned) | Trek — Segafredo | |
| 4 | Amy Pieters | (Ned) | Boels Dolmans Cyclingteam | 0:00:20 |
| 5 | Lotte Kopecky | (Bel) | Lotto Soudal Ladies | |
| 6 | Amalie Dideriksen | (Den) | Boels Dolmans Cyclingteam | |
| 7 | Floortje Mackaij | (Ned) | Team Sunweb | |
| 8 | Kirsten Wild | (Ned) | WNT Rotor Pro Cycling Team | |
| 9 | Romy Kasper | (Ger) | Ale Cipollini | |
| 10 | Jip Van Den Bos | (Ned) | Boels Dolmans Cyclingteam | |
| 11 | Marianne Vos | (Ned) | CCC — Liv | 0:00:36 |
| 12 | Lucinda Brand | (Ned) | Team Sunweb | 0:00:37 |
| 13 | Tiffany Cromwell | (Aus) | Canyon-SRAM Racing | 0:00:43 |
| 14 | Sarah Roy | (Aus) | Mitchelton Scott | 0:01:15 |
| 15 | Chloe Hosking | (Aus) | Ale Cipollini | 0:01:18 |
| 16 | Alice Barnes | (Gbr) | Canyon-SRAM Racing | |
| 17 | Maria Giulia Confalonieri | (Ita) | Valcar Cylance Cycling | |
| 18 | Lotta Pauliina Lepistö | (Fin) | Trek — Segafredo | |
| 19 | Alexis Ryan | (Usa) | Canyon-SRAM Racing | |
| 20 | Malgorzata Jasinska | (Pol) | Movistar Team Women | |
| 21 | Lisa Klein | (Ger) | Canyon-SRAM Racing | |
| 22 | Evy Kuijpers | (Ned) | CCC — Liv | |
| 23 | Roxane Knetemann | (Ned) | Parkhotel Valkenburg | |
| 24 | Aude Biannic | (Fra) | Movistar Team Women | |
| 25 | Elizabeth Banks | (Gbr) | Bigla | |
| 26 | Audrey Cordon Ragot | (Fra) | Trek — Segafredo | |
| 27 | Lisa Brennauer | (Ger) | WNT Rotor Pro Cycling Team | |
| 28 | Lauren Kitchen | (Aus) | FDJ Nouvelle — Aquitaine Futuroscope | 0:01:54 |
| 29 | Alison Jackson | (Can) | Team Tibco — Silicon Valley Bank | |
| 30 | Julie Leth | (Den) | Bigla | |
| 31 | Janneke Ensing | (Ned) | Team Sunweb | |
| 32 | Grace Brown | (Aus) | Mitchelton Scott | |
| 33 | Sofia Bertizzolo | (Ita) | Team Virtu Cycling | |
| 34 | Mieke Kröger | (Ger) | Team Virtu Cycling | |
| 35 | Amber Van Der Hulst | (Ned) | Netherlands | 0:03:00 |
| 36 | Annelies Dom | (Bel) | Lotto Soudal Ladies | 0:03:01 |
| 37 | Rotem Gafinovitz | (Isr) | Canyon-SRAM Racing | |
| 38 | Eva Buurman | (Ned) | Boels Dolmans Cyclingteam | |
| 39 | Roxane Fournier | (Fra) | Movistar Team Women | |
| 40 | Marta Tagliaferro | (Ita) | Hitec Products — Birk Sport | |
| 41 | Ella Harris | (Nzl) | Canyon-Sram Racing | |
| 42 | Soraya Paladin | (Ita) | Ale Cipollini | |
| 43 | Gracie Elvin | (Aus) | Mitchelton Scott | |
| 44 | Danielle Christmas | (Gbr) | Lotto Soudal Ladies | 0:04:11 |
| 45 | Pfeiffer Georgi | (Gbr) | Team Sunweb | |
| 46 | Sandra Alonso Dominguez | (Spa) | Bizkaia — Durango | |
| 47 | Jelena Erić | (Srb) | Ale Cipollini | |
| 48 | Nina Kessler | (Ned) | Team Tibco — Silicon Valley Bank | 0:04:21 |
| DNF | Christine Majerus | (Lux) | Boels Dolmans Cyclingteam | |
| DNF | Karlijn Swinkels | (Ned) | Ale Cipollini | |
| DNF | Nadia Quagliotto | (Ita) | Ale Cipollini | |
| DNF | Nicole Hanselmann | (Swi) | Bigla | |
| DNF | Maria Vittoria Sperotto | (Ita) | Bigla | |
| DNF | Martina Alzini | (Ita) | Bigla | |
| DNF | Valerie Demey | (Bel) | CCC — Liv | |
| DNF | Marta Lach | (Pol) | CCC — Liv | |
| DNF | Jeanne Korevaar | (Ned) | CCC — Liv | |
| DNF | Riejanne Markus | (Ned) | CCC — Liv | |
| DNF | Victorie Guilman | (Fra) | FDJ Nouvelle — Aquitaine Futuroscope | |
| DNF | Coralie Demay | (Fra) | FDJ Nouvelle — Aquitaine Futuroscope | |
| DNF | Emilia Fahlin | (Swe) | FDJ Nouvelle — Aquitaine Futuroscope | |
| DNF | Greta Richioud | (Fra) | FDJ Nouvelle — Aquitaine Futuroscope | |
| DNF | Maëlle Grossetete | (Fra) | FDJ Nouvelle — Aquitaine Futuroscope | |
| DNF | Jessica Allen | (Aus) | Mitchelton Scott | |
| DNF | Lucy Kennedy | (Aus) | Mitchelton Scott | |
| DNF | Nina Buijsman | (Ned) | Parkhotel Valkenburg | |
| DNF | Lorena Wiebes | (Ned) | Parkhotel Valkenburg | |
| DNF | Femke Markus | (Ned) | Parkhotel Valkenburg | |
| DNF | Marit Raaijmakers | (Ned) | Parkhotel Valkenburg | |
| DNF | Esther Van Veen | (Ned) | Parkhotel Valkenburg | |
| DNF | Ingrid Drexel Clouthier | (Mex) | Team Tibco — Silicon Valley Bank | |
| DNF | Kendall Ryan | (Usa) | Team Tibco — Silicon Valley Bank | |
| DNF | Rozanne Slik | (Ned) | Team Tibco — Silicon Valley Bank | |
| DNF | Barbara Guarischi | (Ita) | Team Virtu Cycling | |
| DNF | Trine Schmidt | (Den) | Team Virtu Cycling | |
| DNF | Katarzyna Pawlowska | (Pol) | Team Virtu Cycling | |
| DNF | Lauretta Hanson | (Aus) | Trek — Segafredo | |
| DNF | Abigail Van Twisk | (Gbr) | Trek — Segafredo | |
| DNF | Anna Plichta | (Pol) | Trek — Segafredo | |
| DNF | Elisa Balsamo | (Ita) | Valcar Cylance Cycling | |
| DNF | Marta Cavalli | (Ita) | Valcar Cylance Cycling | |
| DNF | Dalia Muccioli | (Ita) | Valcar Cylance Cycling | |
| DNF | Silvia Persico | (Ita) | Valcar Cylance Cycling | |
| DNF | Ilaria Sanguineti | (Ita) | Valcar Cylance Cycling | |
| DNF | Sarah Rijkes | (Aut) | WNT Rotor Pro Cycling Team | |
| DNF | Erica Magnaldi | (Ita) | WNT Rotor Pro Cycling Team | |
| DNF | Lea Lin Teutenberg | (Ger) | WNT Rotor Pro Cycling Team | |
| DNF | Lara Vieceli | (Ita) | WNT Rotor Pro Cycling Team | |
| DNF | Henrietta Colborne | (Gbr) | Biehler Pro Cycling | |
| DNF | Merel Hofman | (Ned) | Biehler Pro Cycling | |
| DNF | Roos Hoogeboom | (Ned) | Biehler Pro Cycling | |
| DNF | Melanie Klement | (Ned) | Biehler Pro Cycling | |
| DNF | Natalie Van Gogh | (Ned) | Biehler Pro Cycling | |
| DNF | Nienke Wasmus | (Ned) | Biehler Pro Cycling | |
| DNF | Ainara Elbusto Arteaga | (Spa) | Bizkaia — Durango | |
| DNF | Natalie Grinczer | (Gbr) | Bizkaia — Durango | |
| DNF | Luisa Ibarrola Albizua | (Spa) | Bizkaia — Durango | |
| DNF | Isabel Martin Martin | (Spa) | Bizkaia — Durango | |
| DNF | Aroa Gorostiza Ulloa | (Spa) | Bizkaia — Durango | |
| DNF | Grace Garner | (Gbr) | Hitec Products — Birk Sport | |
| DNF | Lucy Garner | (Gbr) | Hitec Products — Birk Sport | |
| DNF | Amalie Lutro | (Nor) | Hitec Products — Birk Sport | |
| DNF | Chanella Stougje | (Ned) | Hitec Products — Birk Sport | |
| DNF | Lonneke Uneken | (Ned) | Hitec Products — Birk Sport | |
| DNF | Demi De Jong | (Ned) | Lotto Soudal Ladies | |
| DNF | Chantal Hoffmann | (Lux) | Lotto Soudal Ladies | |
| DNF | Thi That Nguyen | (Vie) | Lotto Soudal Ladies | |
| DNF | Lourdes Oyarbide Jimenez | (Spa) | Movistar Team Women | |
| DNF | Gloria Rodriguez Sanchez | (Spa) | Movistar Team Women | |
| DNF | Alba Teruel Ribes | (Spa) | Movistar Team Women | |
| DNF | Susanne Andersen | (Nor) | Team Sunweb | |
| DNF | Julia Soek | (Ned) | Team Sunweb | |
| DNF | Eva Bijwaard | (Ned) | Netherlands | |
| DNF | Maaike Boogaard | (Ned) | Netherlands | |
| DNF | Cathalijne Hoolwerf | (Ned) | Netherlands | |
| DNF | Eva Jonkers | (Ned) | Netherlands | |
| DNF | Anne Tauber | (Ned) | Netherlands | |
| DNF | Sara Mustonen | (Swe) | Health Mate — Ladies Team | |
| DNF | Esther Meisels | (Isr) | Health Mate — Ladies Team | |
| DNF | Kathrin Schweinberger | (Aut) | Health Mate — Ladies Team | |
| DNF | Christina Schweinberger | (Aut) | Health Mate — Ladies Team | |
| DNF | Kirstie Van Haaften | (Ned) | Health Mate — Ladies Team | |
| DNF | Kylie Waterreus | (Ned) | Health Mate — Ladies Team | |
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